Billingham 3-95 Leica M

As with most photographers I have a literal closet full of camera bags. Some too big, others too small, etc. The Billingham is fully functional (waterproof, excellent closures) and has there very interesting "press closure" on their larger models which makes the bag usable on the run with things not flying out.
They don't scream CAMERAS INSIDE which many bags do, the understated canvas looking like many luggage bags on the market today.
Better padded than Domke (great bag however), yet much more comfortable than Lowe Pro style bags. They are expensive, but try one, and like me you'll probably buy two or three others in different sizes.

Construction
Waterproof
Comfort

Price

Lowe Pro
Domke

Very good